The FDA is said to have just lately instituted a crack down on weight loss supplements as a result of very bad negative effects and even death connected with some dietary supplements such as ephedra. The ban on ephedra merchandise resulted to the development of so-called ephedra free weight loss supplements, these too have been shown to yield their own fair share of situations and they too might be most likely going to exactly the same fate as ephedra.

These ephedra free medicines have been shown to bring about a rise in heart rate and a couple other unwanted side effects on healthy folks reported by a health authority who was in the study.

The investigation carried out through the University of California at Berkeley was the first one to research the health effects of reformulated weight loss supplements. One of the things analyzed for included high blood pressure and pulse rate of volunteers who were given reformulated weight loss supplements formed from extracts of bitter orange.

Ever since the ban slapped on ephedra by FDA, a growing number of body weight loss product manufactures have switched to extracts of bitter orange. The USB research engaged 20 healthy volunteers, who received single doses of a weight loss supplement or a placebo.

The diet supplements used in the research were Xenadrine EFX and Advantra Z, each of which includes bitter orange extracts. The administered drug was shown to cause a rise in heart pulse rate as high as 16 beats in one minute. The Thermogenic Xenadrine EFX for example was shown to rev up heart rate by 13 per cent, an element that makes it almost identical in performance to ephedra.

Bitter orange extracts have synephrine, a component specific to over 90% of citrus fruits but found in greater concentrations in fruits such as Sour orange, Zhi shi and bitter orange and which happens to be commonly used as a relief medication in the management of respiratory tract congestion and hypertension. Xenadrine EFX features a stimulant in the element, usually caffeine. The quantity of caffeine is Xenadrine is approximated to be the same as 3 coffee cups. This is the component the cause the boost in blood pressure and patients using this product are informed against over dosage.

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